global total™ LP Medium
A pioneer in single-step media
formulation
Trusted for decades, LifeGlobal media delivers consistent, reliable performance for your laboratory.
LifeGlobal medium is the first commercially available single-step medium for IVF
Consists of well-defined media components in concentrations determined via thorough and methodical optimization4
Formulation minimizes oxidative stress and culture-induced stresses2,3,5
SAGE 1-Step™ Medium
A refined, robust, single-step medium
with hyaluronan
SAGE 1-Step medium supports consistency, reliability, and confidence in the laboratory.
The combination of hyaluronan and human serum albumin (HSA) in culture medium has been shown to significantly increase embryo development2,6
Features a high ratio of magnesium to calcium, which is highly beneficial to embryo development and viability7
Increased levels of antioxidants provide a protective effect during embryo culture3
The Science of Continuous Culture
Our single-step media solutions are engineered to reduce environmental stress and streamline your laboratory workflow.8,9 By utilizing a continuous culture system, the need for dish handling and media changes, minimizing the chance of fluctuations in temperature and pH.8,9
Our media formulations are designed with the nutritional needs of the human embyro in mind,1,2 giving you the confidence that your embryos are supported at every critical stage of development.
Partner With Us for Expert Support
We offer more than just a premium product portfolio. Our team of specialists is available to help you seamlessly integrate our culture media into your existing workflow. From pH testing and media evaluations to hands-on training and expert troubleshooting, we provide ongoing education to enhance your lab efficiency.
Take the next step
Ready to optimize your culture system?
Contact your local CooperSurgical representative today to learn more about integrating our products into your laboratory.
References
- Quinn, P. (2012). Embryo Culture: Methods and Protocols. Methods in Molecular Biology, Vol. 912.
- Lane, M. and Gardner, D.K., (2007). Dynamics of pre-implantation embryo metabolism, Best Practice & Research Clinical Obstetrics and Gynaecology, 21(1), pp. 83-100.
- Agarwal, A., et al. (2014). Role of antioxidants in assisted reproductive techniques, Reproductive Biology and Endocrinology, 12(112).
- Summers, M.C. (2013). A brief history of the development of the KSOM family of media. Journal of Assisted Reproduction and Genetics, 30(8), pp.995–999.
- Sciorio, R. and Rinaudo, P., (2023). Culture conditions in the IVF laboratory: state of the ART and possible new directions. Journal of Assisted Reproduction and Genetics, 40(11), pp.2591–2607.
- Fouladi-Nashta, A.A., et al. (2007). Impact of Dietary Fatty Acids on Oocyte Quality and Development in Lactating Dairy Cows1. Biology of Reproduction, 77(1), pp.9–17.
- Lane, M. and Gardner, D.K. (2000). Regulation of ionic homeostasis by mammalian embryos. Seminars in reproductive medicine,18(2), pp.195–204.
- Sfontouris, I.A., et al., (2016) Blastocyst culture using single versus sequential media in clinical IVF: a systematic review and meta-analysis of randomized controlled trials. Journal of Assisted Reproduction and Genetics, 33(10), pp. 1261–1272.
- Reed, M.L., et al., (2009) Continuous uninterrupted single medium culture without medium renewal versus sequential media culture: a sibling embryo study. Fertility and Sterility, 92(5), pp. 1783–1786.
