SAGE 1-Step™

SAGE 1-Step™ 2

A single step medium for uninterrupted embryo culture

The information below represents the SAGE 1-Step HSA containing hyaluronan.

SAGE 1-Step SPS does not contain hyaluronan, please see the datasheet for SAGE  1-Step SPS for information concerning this product.

SAGE 1-Step is a continuous culture medium that has been developed with a strong focus on robustness. It allows uninterrupted culture following IVF or ICSI insemination through to the blastocyst stage, and is ideal for use with time lapse technology.

Key Features

  • Hyaluronan to promote cryo survival and embryo implantation
  • A stable glutamine source supporting a reduced ammonium build-up
  • Optimized ionic composition and energy substrates supporting uninterrupted continuous culture


SAGE 1-Step HSA is available for sale in Europe, the U.S.A, Canada and Australia as well as selected countries in the rest of the world.
SAGE 1-Step SPS is available for sale in the U.S.A and selected countries in the rest of the world. It is not available for sale in Europe.

Product codes

ProductOrder CodeSizeHSA mg/mlSPS mg/mlShelf Life Guarantee*
SAGE 1-Step™, with HSA and phenol red6701001010 ml5 mg/mLMinimum 8 weeks
SAGE 1-Step™, with HSA and phenol red6701006060 ml5 mg/mLMinimum 8 weeks
SAGE 1-Step™, with SPS and phenol red6702001010 ml5 mg/mLMinimum 8 weeks
SAGE 1-Step™, with SPS and phenol red6702006060 ml5 mg/mLMinimum 8 weeks
*Minimum time to expiry

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  • Magnesium sulphate
  • Potassium chloride
  • Potassium phosphate
  • Sodium chloride
  • Amino acids
  • L-alanyl-L-glutamine
  • Calcium-L-lactate
  • Glucose · Sodium pyruvate
  • Sodium bicarbonate
  • EDTA · Gentamicin
  • Phenol red

SAGE 1-Step™ with HSA (6701) only:

  • Sodium hyaluronate
  • Human Serum Albumin

SAGE 1-Step™ with SPS (6702) only:

  • Serum Protein Supplement (SPS)
  • CE marked (CE 0543): SAGE 1-Step with HSA only
  • Cleared by the FDA
  • Canada Medical Device licensed
  • Sterility tested (Ph. Eur., USP)
  • Osmolality tested (Ph. Eur., USP)
  • pH tested (Ph. Eur., USP)
  • Endotoxin tested ≤ 0.15 EU/ml (Ph. Eur., USP)
  • Mouse Embryo Assay (MEA)




Creating the optimal environment for human embryology procedures


Embryo Transfer

A comprehensive range of embryo transfer products to suit your needs

Want unlimited First line support?

All our USA and Europe Customers get free unlimited first line support with a service contract.

Support & Compliance

Our global team is committed to providing the highest standards of service and support.

SAGE 1-Step™ 6

Batch Certificates

Use this tool to enter your batch number and download the corresponding certificate of analysis.

SAGE 1-Step™ 7


We offer a range of contract options to suit your needs: preventative maintenance and service, reliable access to spare parts, product training, and online handling of service requests.

SAGE 1-Step™ 8

Hardware Warranty

Submit your Product Warranty Card online by completing our quick and easy form.

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We’d love to hear from you. How can we help?