ORIGIO® Gradients and ORIGIO® Sperm Wash

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Media for sperm preparation with innovative formulation, drawing on the latest scientific knowledge of sperm function. 

Mimicking natural conditions, supporting sperm motility and functions,1-8protecting spermatozoa from oxidative damage9-12 and osmotic stress during preparation.13-14

ORIGIO® Gradients – media for the efficient separation of motile spermatozoa from the ejaculate by the density gradient method. Ready-to-use ORIGIO® Gradient 40/80 kits, designed to minimize osmotic stress during preparation, as well as classical 90% and 100% ORIGIO® Gradient solutions for custom-made gradients after dilution with ORIGIO® Sperm Wash.

ORIGIO® Sperm Wash – media for washing of spermatozoa, the isolation of motile viable spermatozoa by swim-up method, dilution of ORIGIO® Gradients, and holding spermatozoa for IUI procedures. Designed to support sperm motility and physiologic functions.

Availability

This product is available for sale in Europe, the USA as well as selected countries in the rest of the world.

Key Features

ORIGIO Gradients and ORIGIO Sperm Wash have a unique combination of advantages:

  • High pH of 8.0-8.5 to mimic in vivo physiological conditions and stimulate higher motility1,2,5
  • High concentration of bicarbonate to support optimal sperm function1-4
  • 3 antioxidants (EDTA, taurine, citrate) added to minimize formation of reactive oxygen species and protect spermatozoa from oxidative damage9-12
  • Fully HEPES buffered to use outside a CO2 controlled environment. Requires no pre-equilibration.
  • Shelf life after opening: 28 days

ORIGIO® Gradient 40/80 specifically:

  • Tailored osmolality, differentiated through layers to minimize osmotic stress to spermatozoa13,14

ORIGIO® Sperm Wash specifically:

  • High concentration of albumin to support sperm physiology and protect from oxidative stress6
  • Can be used for IUI, IVF, and ICSI

Learn more about best practice in sperm preparation from our webinar

Tips & Tricks of Sperm Preparation

with Matthew Tomlinson, PhD, Consultant Scientist in Andrology and
Dave Morroll, PhD, CooperSurgical’s Director of Clinical Support

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Optimizing Therapeutic Sperm Washing

By Mathew Tomlinson PhD

Why are there clear differences in sperm progression and velocity between products? Read more about the scientific data underlying our andrology media formulation.

Read the article here
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Supporting Sperm Function and Why You Should Care

By Dave Morroll PhD

How to support and protect sperm during prepara

Read the article here

HBA® Assay

For fast evaluation of the percentage of mature motile spermatozoa in semen samples.

Learn More
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PICSI® Dish

For mature sperm selection for ICSI. Recently published clinical data confirm sperm selection with PICSI dish can help to mitigate the negative effect of advanced maternal age.

Learn More
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SpermSlow™

For one step immobilization and selection of mature spermatozoa for ICSI without the use of PVP.

Learn More

Product codes

ProductOrder CodeSizeHSA mg/mlShelf Life Guarantee
ORIGIO Gradient 1008400006060mlMinimum 12 weeks
ORIGIO Gradient 100840020602 x 60mlMinimum 12 weeks
ORIGIO Gradient 100840041254 x 125mlMinimum 12 weeks
ORIGIO Gradient™ 908401006060ml5 mg/mLMinimum 12 weeks
ORIGIO Gradient™ 40/80840220602 x 60ml5 mg/mLMinimum 12 weeks
ORIGIO Gradient™ 40/80840220102 x 10ml5 mg/mLMinimum 12 weeks
ORIGIO Gradient™ 40/808402121012 x 10ml5 mg/mLMinimum 12 weeks
ORIGIO Sperm Wash8405006060ml10 mg/mLMinimum 12 weeks
ORIGIO Sperm Wash840550605 x 60ml10 mg/mLMinimum 12 weeks
ORIGIO Sperm Wash8405101010 x 10ml10 mg/mLMinimum 12 weeks

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Specifications – Sperm Wash

Sterility tested (Ph.Eur., USP)
Osmolality tested (Ph.Eur., USP)
pH tested (Ph.Eur., USP)
Endotoxin tested < 0.15 EU/ml (Ph.Eur., USP) HSA analysis (Ph.Eur., USP) Sperm survival test Specifications – Gradients

Sterility tested (Ph.Eur., USP)
Osmolality tested (Ph.Eur., USP)
pH tested (Ph.Eur., USP)
Endotoxin tested ≤ 0.8 EU/ml (Ph.Eur., USP)
HSA analysis (Ph.Eur., USP)
Sperm survival test

Gradient 100 Composition
Silane-coated silica particles
Glucose
Sodium pyruvate
Physiological salts
Taurine
HEPES
Sodium bicarbonate

Gradient 90, 40/80 Composition
Silane-coated silica particles
Gentamicin sulphate 10 µg/ml
Human Serum albumin (HSA)
Glucose
Sodium pyruvate
Physiological salts
Taurine
HEPES
Sodium bicarbonate

Sperm Wash Composition
Gentamicin sulphate 10 µg/ml
Human Serum albumin (HSA)
Glucose
Sodium pyruvate
Physiological salts
Taurine
HEPES
Sodium bicarbonate

Procedures

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Andrology & IUI

Optimize your success by selecting the highest quality sperm

Want unlimited First line support?

All our USA and Europe Customers get free unlimited first line support with a service contract.

Support & Compliance

Our global team is committed to providing the highest standards of service and support.

Batch Certificates

Use this tool to enter your batch number and download the corresponding certificate of analysis.

Service

We offer a range of contract options to suit your needs: preventative maintenance and service, reliable access to spare parts, product training, and online handling of service requests.

Hardware Warranty

Submit your Product Warranty Card online by completing our quick and easy form.

Get In Touch With Us

We’d love to hear from you. How can we help?